![]() ![]() The expression levels were higher at the end of each instar and at the beginning of each molt than at other periods, coinciding with the pulse of ecdysone and BR-C as a whole. The bmo-let-7 was very lowly expressed in ova harvested from newborn unmated female adult and in individuals from the first molt to the early third instar, highly expressed after the third molt, and the most abundant expression was observed after mounting, particularly after pupation. Sequence logo and phylogenetic tree show that they are not only conserved but diversify to some extent among some species. All known members of this family share the same nucleotides at ten positions within the mature sequences. One member of let-7 family has been identified in silkworm computationally and experimentally. For a better understanding of the conservation and functions of let-7, we seek to explore how it is expressed in the silkworm ( Bombyx mori). Ecdysone and Broad-Complex are required for the temporal expression of let-7 in Drosophila melanogaster. let-7 has been thought to trigger the onset of adulthood across animal phyla. ![]() Lin-4 and let-7, the two founding members of heterochronic microRNA genes, are firstly confirmed in Caenorhabditis elegans to control the proper timing of developmental programs in a heterochronic pathway.
0 Comments
Leave a Reply. |